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PICOT Questions

Creating a Search Strategy from a PICOT Question

Population

Avoid highly specific, narrow age-ranges. 

Include relevant terms for our population, but take care to avoid redundancy if the population is implied by the intervention or outcome, or vice versa.

  • Take the following PICO, for example
    • P: Smokers
    • I: Wellbutrin
    • C: No Wellbutrin
    • O: Smoking cessation
  • The search Smokers AND Wellbutrin AND Smoking Cessation  would be redundant. The population (smokers) is implied by the outcome (smoking cessation).

Intervention

Intervention is generally the focus of your search, but do not include directional terms like improve, reduce, increase, mitigate that could result in confirmation bias. 

Comparison

If your comparison is usual care or no treatment, do not include this in your search strategy. 

Not all PICO questions have a comparison (prognosis and meaning questions often don’t include a C)

It’s ok just to look at the efficacy of an intervention! 
 

Outcome

Similar to population, avoid redundancy (if you’re population is individuals with high blood pressure and your intervention is a statin, your outcome is probably implied)

Similar to intervention, avoid directional terms (improve, reduce, increase, mitigate)

Time

Many PICOT questions do not include a time component. 

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